Deadlock cleanse items
Removes debuffs already on you. Against a lockdown chain a cleanse is worth more than resistance, which only shortens what lands.
8 items on patch 09-16-2026. Pick a tier, then an item, for what it does and when to buy it.
Vitality
6 items3,200 souls each
Counterspell Counterspell +23s Cooldown +20 Spirit Power +6s Buff Duration +0.8s Spell Parry Duration +50 Bonus Health +5 Spirit Power Documented Charges your parry so that the next one blocks the damage and effects of an enemy ability or item outright, healing and buffing you when it lands.
Buy when: Buy against telegraphed single-target ultimates and hex-style point-and-click abilities you can read and parry.
0.8s parry window; on a successful spell parry: 150 heal, +20 Spirit Power, +1.75m Move Speed for 6s; 23s cooldown; +50 Bonus Health, +5 Spirit Power
Watch out: Multiple abilities can be parried in the window, but the heal and buffs only apply from the first
Dispel Magic Dispel Magic +45s Cooldown +10% Spirit Resist +3s Buff Duration +250 HP Healed On Activate Documented Purges every non-ultimate debuff currently on you and, if it removed anything, heals you and grants move speed. It is the main hard cleanse in the game.
Buy when: Buy when enemy debuffs — slows, silences, anti-heal, disarms, hexes — are what is killing you rather than raw damage.
45s cooldown; 250 heal; +2m Move Speed for 3s; +10% Spirit Resist
Watch out: Cannot be used while stunned or asleep
6,400 souls each
Cheat Death Cheat Death +90s Cooldown +4.5s Death Immunity Duration +200 Bonus Health +15% Bullet Resist -60% Damage Reduction -60% Healing Reduction -60% Healing Reduction Documented When you would die, you instead survive with temporary invulnerability and all non-Stun debuffs cleared — at the cost of heavily reduced damage and healing during the window.
Buy when: Buy when you are being assassinated in every fight — it converts one death per 90 seconds into an escape window.
4.5s death immunity, 90s cooldown, -60% damage and -60% healing during it; +200 Bonus Health, +15% Bullet Resist
Watch out: Clears all non-stun debuffs when it triggers
Divine Barrier Divine Barrier +45s Cooldown +0.2s Cast Delay +1.5 Out of Combat Regen +6s Buff Duration +600 Barrier +10% Ability Range +10% Radius Documented Strips all non-Stun debuffs from an ally (or yourself) at range and gives them a large barrier and move speed. It is the only ranged cleanse in the game.
Buy when: Buy on supports to cleanse a focused ally's debuffs and shield them through a burst window from across the fight.
600 Barrier, +2.75m Move Speed for 6s, 40m cast range, 45s cooldown (halved when cast on allies); +10% Ability Range, +1.5 out-of-combat regen
Watch out: Removes non-stun debuffs only — stuns are not cleansed
Indomitable Indomitable +55s Cooldown +10s Duration +10% Bullet Resist +10% Spirit Resist +20s Cooldown On Apply +2 Out of Combat Regen Documented The next hard crowd-control effect that hits you is automatically cleansed, and you get a barrier and a big cooldown refund for free. Unlike 
Unstoppable Unstoppable +60s Cooldown +5.5s Duration +125 Bonus Health +25% Debuff Resist Builds from Debuff Reducer it needs no reaction.
Buy when: Buy when enemy CC lands faster than you can react — it is the automatic, no-timing-required anti-lockdown item.
+10% Bullet Resist, +10% Spirit Resist, +2 out-of-combat regen; auto-cleanses the next Stun/Chain/Immobilize/Sleep/Silence, grants 325 Barrier (+2.0 spirit scaling) for 10s and -20% on all ability cooldowns; 55s cooldown
Unstoppable Unstoppable +60s Cooldown +5.5s Duration +125 Bonus Health +25% Debuff Resist Documented On activation you suppress your current negative effects and become flatly immune to Stun, Silence, Sleep, Root and Disarm for several seconds. It is the definitive answer to a crowd-control chain.
Buy when: Buy when enemy lockdown is the reason you lose fights — it lets you walk through a full CC chain and still deal damage.
+25% Debuff Resist, +125 Bonus Health; active: 5.5s immunity to Stun/Silence/Sleep/Root/Disarm, 60s cooldown
Watch out: Cannot be used while already stunned or asleep — it must be pre-cast
Spirit
2 items6,400 souls each
Cursed Relic Cursed Relic +55s Cooldown +3.25s Duration +0.1s Cast Delay -25% Damage Penalty Documented Curses a single enemy: it interrupts them, silences them, disarms them, blocks item use and strips all their non-ultimate buffs. Nothing else in the game removes an enemy from a fight so completely — but holding it costs you damage.
Buy when: Buy to shut down one enemy carry or to cancel a game-deciding ultimate outright.
3.25s curse (interrupt, Silence, Disarm, item lockout, removes non-ultimate buffs) plus a 0.3s stun and heavy slow; 20m cast range, 55s cooldown; -25% of your own damage while the curse runs
Watch out: Since 30 Jan 2026 it no longer grants weapon damage and instead applies an 8% total damage penalty while held; it also lost its spirit resist and health bonuses
Scourge Scourge +35s Cooldown +10s Duration +0.25s Cast Delay +40% Spirit Resist +100 Bonus Health +20% Debuff Resist Documented Buffs a friendly target (including yourself) with heavy Spirit Resist and debuff resist plus a damaging aura, and reduces debuffs already on them. It is a team-wide defensive save.
Buy when: Buy on supports to harden a focused ally against a caster team while adding pressure damage.
2.3% max health/s aura damage in a 10m radius, +40% Spirit Resist, +20% Debuff Resist for 10s; 35m cast range, 35s cooldown; +100 Bonus Health
Other things to buy for
Each of these lists the items that provide it, the same way.