Deadlock healing reduction items
Cuts how much an enemy heals. Against a team that heals through your damage this stops being situational and becomes part of the damage build.
6 items on patch 09-16-2026. Pick a tier, then an item, for what it does and when to buy it.
Weapon
2 items3,200 souls each
Toxic Bullets Toxic Bullets -35% Healing Reduction -35% Healing Reduction Documented Bullets build up a bleed that damages a share of the target's maximum health and, crucially, cuts their healing while it runs.
Buy when: The gun-hero answer to enemy Lifesteal and big-health frontliners — buy it when an enemy is out-healing your damage.
1.9% max health per second bleed (+0.006 spirit scaling), 35% Healing Reduction, 4s duration; build-up per bullet varies by hero
Watch out: Bleed does not build from melee attacks
6,400 souls each
Crippling Headshot Crippling Headshot +125 Bonus Health -16% Bullet Resist -16% Spirit Resist -35% Healing Reduction -35% Healing Reduction +12s Debuff Duration Documented A headshot debuffs the target hard: both resistances drop and their healing is cut for a long window. It is simultaneously an armour-shred, an anti-heal and a focus-fire tool.
Buy when: Buy when one durable, self-healing enemy is the focus of every fight and you can land headshots.
On headshot: approx -17% Bullet Resist, -17% Spirit Resist, -35% Healing Reduction for 12s; +125 Bonus Health
Watch out: The triggering headshot itself is dealt before the resist reduction applies
Vitality
2 items1,600 souls each
Healbane Healbane +8s Duration +7 Spirit Power -35% Healing Reduction -35% Healing Reduction +275 Heal On Hero Kill Documented Your Spirit Damage applies healing reduction to the target, and you get a large heal if a hero dies under the effect.
Buy when: The cheapest and most common anti-heal buy — take it the moment an enemy's Lifesteal or a support's healing is out-pacing your damage.
35% Healing Reduction for 8s; 275 heal on hero kill under the effect; +7 Spirit Power
Watch out: Only applies through spirit damage, not plain bullet damage
6,400 souls each
Inhibitor Inhibitor +150 Bonus Health +5s Debuff Duration -30% Damage Penalty +10% Weapon Damage -40% Healing Reduction -40% Healing Reduction Documented Your bullets build up a debuff that both cuts the target's outgoing damage and applies heavy healing reduction — the strongest single answer to a self-sustaining carry.
Buy when: Buy on a gun hero when one enemy is both out-damaging and out-healing your team — it hits both problems at once.
-30% enemy Damage and -40% Healing Reduction for 5s at full build-up; +10% Weapon Damage, +150 Bonus Health; build-up per shot varies by hero
Watch out: The damage penalty does not apply to spirit damage from an enemy with Unstoppable active; the healing reduction always applies
Spirit
2 items3,200 souls each
Decay Decay +30s Cooldown +12s Duration +0.1s Cast Delay +8 Spirit Power -50% Healing Reduction -50% Healing Reduction +65 Bonus Health Documented A targeted damage-over-time curse that deals damage based on the victim's health and, most importantly, cuts their healing by half for a long window. It is the strongest dedicated anti-heal in the spirit tree.
Buy when: Buy when an enemy is healing through your damage and you want a point-and-click answer that does not rely on landing bullets.
-50% Healing Reduction for 12s; 1.95 spirit damage/s (+0.003 scaling); 20m cast range, 30s cooldown; +8 Spirit Power, +65 Bonus Health
Watch out: Healing reduction raised -45% -> -50% on 6 Mar 2026
6,400 souls each
Spirit Burn Spirit Burn +6% Ability Range +6% Radius +500 Damage Threshold +50 Explosion Damage +8s Debuff Duration -70% Healing Reduction -70% Healing Reduction +20s Immunity Duration Documented A big hit of Spirit Damage detonates into an explosion and a long burn that applies extremely heavy healing reduction — the most severe anti-heal in the game.
Buy when: Buy on a heavy burst caster against an enemy whose Lifesteal or healing is the win condition.
Triggers above a 500 damage threshold: 50 explosion damage, 24 (+0.06 scaling) burn damage/s for 8s, -70% Healing Reduction; 20s immunity per target; +6% Ability Range
Watch out: 20s immunity per target means you cannot reapply it repeatedly to the same enemy
Other things to buy for
Each of these lists the items that provide it, the same way.