Healing and lifesteal

Items that answer this

• Healbane vitality · T2 · 1,600 Verified

  Your spirit damage applies healing reduction to the target, and you get a large heal if a hero dies under the effect.

  Buy when: The cheapest and most common anti-heal buy — take it the moment an enemy's lifesteal or a support's healing is out-pacing your damage.

  Gotcha: Only applies through spirit damage, not plain bullet damage

• Decay spirit · T3 · 3,200 Verified

  A targeted damage-over-time curse that deals damage based on the victim's health and, most importantly, cuts their healing by half for a long window. It is the strongest dedicated anti-heal in the spirit tree.

  Buy when: Buy when an enemy is healing through your damage and you want a point-and-click answer that does not rely on landing bullets.

  Gotcha: Healing reduction raised -45% -> -50% on 6 Mar 2026

• Toxic Bullets weapon · T3 · 3,200 Verified

  Bullets build up a bleed that damages a share of the target's maximum health and, crucially, cuts their healing while it runs.

  Buy when: The gun-hero answer to enemy lifesteal and big-health frontliners — buy it when an enemy is out-healing your damage.

  Gotcha: Bleed does not build from melee attacks

• Crippling Headshot weapon · T4 · 6,400 Verified

  A headshot debuffs the target hard: both resistances drop and their healing is cut for a long window. It is simultaneously an armour-shred, an anti-heal and a focus-fire tool.

  Buy when: Buy when one durable, self-healing enemy is the focus of every fight and you can land headshots.

  Gotcha: The triggering headshot itself is dealt before the resist reduction applies

• Inhibitor vitality · T4 · 6,400 Verified

  Your bullets build up a debuff that both cuts the target's outgoing damage and applies heavy healing reduction — the strongest single answer to a self-sustaining carry.

  Buy when: Buy on a gun hero when one enemy is both out-damaging and out-healing your team — it hits both problems at once.

  Gotcha: The damage penalty does not apply to spirit damage from an enemy with Unstoppable active; the healing reduction always applies

• Spirit Burn spirit · T4 · 6,400 Verified

  A big hit of spirit damage detonates into an explosion and a long burn that applies extremely heavy healing reduction — the most severe anti-heal in the game.

  Buy when: Buy on a heavy burst caster against an enemy whose lifesteal or healing is the win condition.

  Gotcha: 20s immunity per target means you cannot reapply it repeatedly to the same enemy

Heroes that cause this

• Abrams
• Apollo
• Bebop
• Calico
• Celeste
• Dynamo
• Graves
• Haze
• Infernus
• Ivy
• Kelvin
• Lady Geist
• Lash
• McGinnis
• Mina
• Mirage
• Mo & Krill
• Paige
• Rem
• Silver
• Victor
• Viscous
• Warden
• Wraith
• Yamato

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Which of these is worth a slot depends on how many of the six enemies really press this. The tool works that out from the lineup.